BRCA2 gene implicated in rare but lethal prostate cancer

Findings published in renowned journal Nature Communications



January 9, 2017 – TORONTO, ON – Canadian scientists have discovered a link between an inherited mutation in the BRCA2 gene and a deadly form of prostate cancer. Funded by Prostate Cancer Canada and led by Dr. Robert Bristow of the Princess Margaret Cancer Centre in Toronto, the findings were published today in Nature Communications: 


Dr. Robert Bristow of the Princess Margaret Cancer Centre in Toronto discusses the newly
published BRCA2 paper in Nature Communications

Known more commonly for its role in breast and ovarian cancers, healthy BRCA2 genes protect against tumours by producing proteins that help repair damaged genes. Mutations in these genes, however, can result in gene damage that does not get repaired properly and leads to aggressive cancers.

“Thanks to the commitment and generosity of our loyal Canadian donors, we are continually striving towards a world in which we will be able to personalize care for all men diagnosed with the most common cancer in men,” explained Dr. Stuart Edmonds, Vice President of Research, Health Promotion and Survivorship at Prostate Cancer Canada. “The BRCA2 project is an example of yet another significant development to that end.”

Full Article: http://www.nature.com/articles/ncomms13671
Related Study: Genetic Association with Aggressive Prostate Cancer Discovered

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For more information please contact:
Adam Miller
Manager, Communications
Prostate Cancer Canada
416 441 2131 ext. 235
adam.miller@prostatecancer.ca
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