//before events button_psab.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = PSABpage.join(""); } button_initial.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = ISBpage.join(""); } button_initext.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = EXTBpage.join(""); } button_repeat.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = RBpage.join(""); } button_saturation.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = SBpage.join(""); } button_mort120.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = MORT120page.join(""); } //------------------------------------------ //bf I events button_gsu.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = GSUpage.join(""); } button_ece.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = ECEpage.join(""); } button_lsvi.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = LSVIpage.join(""); } button_lni.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = LNIpage.join(""); } button_lrmv.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = LRMVpage.join(""); } button_plnd.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = PLNDpage.join(""); } button_obt.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = OBTpage.join(""); } //---------------------------------------------- //bf II events button_insig.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = INSIGpage.join(""); } button_tzpz.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = TZPZpage.join(""); } button_dmar.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = DMARpage.join(""); } button_ysat.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = YSATpage.join(""); } //---------------------------------------------- //after surgery events button_loc.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = LOCpage.join(""); } button_dis.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = DISpage.join(""); } button_pcass.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = PCASSpage.join(""); } button_psa.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = PSApage.join(""); } //---------------------------------------------- //after psa relapse events button_meta.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = METApage.join(""); } button_rpht.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = RPHTpage.join(""); } button_prec.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = PRECpage.join(""); } //---------------------------------------------- // hormone failure events button_aipc.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = AIPCpage.join(""); } button_pdt.onClick = function(){ tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); container.element().innerHTML = PDTpage.join(""); } //---------------------------------------------- //print button button_print.onClick = function(){ window.print(); } //------------------------------------------ // ISB events button_isb_calculate.onClick = function(){ var error = 0; var error_age = 0; var error_dre = 0; var error_psa = 0; var error_fpsa = 0; if (input_isb_age.getControlText() == "between 10 and 90" || input_isb_age.getControlText() < 10 || input_isb_age.getControlText() > 90 || !isNumeric(input_isb_age.getControlText())){ error_age = 1; error = 1; } if (input_isb_psa.getControlText() == "up to 50"|| input_isb_psa.getControlText() < 0 || input_isb_psa.getControlText() > 50 || !isNumeric(input_isb_psa.getControlText())){ error_psa = 1; error = 1; } if ((input_isb_fpsa.getControlText() != "up to 100" && !isNumeric(input_isb_fpsa.getControlText())) || input_isb_fpsa.getControlText() < 0 || input_isb_fpsa.getControlText() > 100){ error_fpsa = 1; error = 1; } if (combo_isb_dre.getControlText() == "Select"){ error_dre = 1; error = 1; } if (error) { if (error_age) alert("please fill in the age field properly"); else if (error_dre) alert("please fill in the DRE field properly"); else if (error_psa) alert("please fill in the PSA field properly"); else if (error_fpsa) alert("please fill in the Free PSA field properly"); } else { if (input_isb_fpsa.getControlText() == "up to 100") { var age; var dre; var psa; var p,z, kE; age = input_isb_age.getControlText(); psa = input_isb_psa.getControlText(); if (combo_isb_dre.getControlText() == "Suspicious") dre = 1; if (combo_isb_dre.getControlText() == "Normal") dre = 0; kE = 2.718281828459045235360287471352; z = (1.24651 * dre) + (0.05602 * psa) + (0.02058 * age) - 3.0061; p = 100 * (1 / (1 + Math.pow(kE,-z))); p = roundNumber(p,1); result_isb_1.setControlText("The probability of finding prostate cancer"); result_isb_2.setControlText("during an initial sextant biopsy is "); result_isb_2b.setControlText(""+p+"%"); result_isb_3.setControlText("Please discuss this probability with your physician."); result_isb_4.setControlText("This percentage needs to be interpreted in context"); result_isb_5.setControlText("of your age, general health and several other"); result_isb_6.setControlText("considerations."); container.element().innerHTML = ISBpageResult.join(""); tabs.setSelectedItems([0]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } else { var age; var dre; var psa; var fpsa; var p,z, kE; age = input_isb_age.getControlText(); psa = input_isb_psa.getControlText(); fpsa = input_isb_fpsa.getControlText(); if (combo_isb_dre.getControlText() == "Suspicious") dre = 1; if (combo_isb_dre.getControlText() == "Normal") dre = 0; kE = 2.718281828459045235360287471352; z = (1.82162 * dre) + (0.02858 * psa) + (0.02436 * age) - (0.0868001 * fpsa) - 1.01469; p = 100 * (1 / (1 + Math.pow(kE,-z))); p = roundNumber(p,1); result_isb_1.setControlText("The probability of finding prostate cancer"); result_isb_2.setControlText("during an initial sextant biopsy is "); result_isb_2b.setControlText(""+p+"%"); result_isb_3.setControlText("Please discuss this probability with your physician."); result_isb_4.setControlText("This percentage needs to be interpreted in context"); result_isb_5.setControlText("of your age, general health and several other"); result_isb_6.setControlText("considerations."); container.element().innerHTML = ISBpageResult.join(""); tabs.setSelectedItems([0]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } } question_isb_age.onClick = function(){ window.open('/local/files/pcat/glossary/Age_at_bopsy.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_isb_dre.onClick = function(){ window.open('/Tools/local/files/pcat/glossary/DRE.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_isb_psa.onClick = function(){ window.open('/local/files/pcat/glossary/PSA.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_isb_fpsa.onClick = function(){ window.open('/local/files/pcat/glossary/Percent_free_PSA.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } input_isb_age.onControlActivated = function(event){ if (input_isb_age.getControlText() == "between 10 and 90") { input_isb_age.setControlText(""); } } input_isb_age.onControlDeactivated = function(event){ if (input_isb_age.getControlText() == "") { input_isb_age.setControlText("between 10 and 90"); } } input_isb_psa.onControlActivated = function(event){ if (input_isb_psa.getControlText() == "up to 50") { input_isb_psa.setControlText(""); } } input_isb_psa.onControlDeactivated = function(event){ if (input_isb_psa.getControlText() == "") { input_isb_psa.setControlText("up to 50"); } } input_isb_fpsa.onControlActivated = function(event){ if (input_isb_fpsa.getControlText() == "up to 100") { input_isb_fpsa.setControlText(""); } } input_isb_fpsa.onControlDeactivated = function(event){ if (input_isb_fpsa.getControlText() == "") { input_isb_fpsa.setControlText("up to 100"); } } // end of ISB events //-------------------------------------------------------------- // RB events button_rb_calculate.onClick = function(){ var error = 0; var error_age = 0; var error_dre = 0; var error_psa = 0; var error_fpsa = 0; var error_bxs = 0; var error_volsmpl = 0; var error_pvol = 0; var error_smpld = 0; var error_volsmpl2 = 0; if ( input_rb_age.getControlText() == "between 45 and 85" || input_rb_age.getControlText() < 45 || input_rb_age.getControlText() > 85 || !isNumeric(input_rb_age.getControlText()) ){ error_age = 1; error = 1; } if ( input_rb_psa.getControlText() == "up to 50"|| input_rb_psa.getControlText() < 0 || input_rb_psa.getControlText() > 50 || !isNumeric(input_rb_psa.getControlText()) ){ error_psa = 1; error = 1; } if ( input_rb_fpsa.getControlText() == "up to 100" || input_rb_fpsa.getControlText() < 0 || input_rb_fpsa.getControlText() > 100 || !isNumeric(input_rb_fpsa.getControlText()) ){ error_fpsa = 1; error = 1; } if ( input_rb_pbx.getControlText() == "between 2 and 7" || input_rb_pbx.getControlText() < 2 || input_rb_pbx.getControlText() > 7 || !isNumeric(input_rb_pbx.getControlText()) ){ error_bxs = 1; error = 1; } if ( input_rb_pvol.getControlText() == "up to 220" && input_rb_smpld.getControlText() == "up to 22" ){ error_volsmpl = 1; error = 1; } if ( input_rb_pvol.getControlText() < 0 || input_rb_pvol.getControlText() > 220 || (input_rb_pvol.getControlText() != "up to 220" && !isNumeric(input_rb_pvol.getControlText()) ) ){ error_pvol = 1; } if ( input_rb_smpld.getControlText() < 0 || input_rb_smpld.getControlText() > 22 || ( input_rb_smpld.getControlText() != "up to 22" && !isNumeric(input_rb_smpld.getControlText()) ) ){ error_smpld = 1; } if (combo_rb_dre.getControlText() == "Select"){ error_dre = 1; error = 1; } if ( ( input_rb_pvol.getControlText() >= 0 && input_rb_pvol.getControlText() <= 220 & isNumeric(input_rb_pvol.getControlText()) != 0 ) && ( input_rb_smpld.getControlText() >= 0 && input_rb_smpld.getControlText() <= 22 && isNumeric(input_rb_smpld.getControlText()) != 0 ) ){ error_volsmpl2 = 1; error = 1; } if ( (error_pvol || error_smpld) ) error = 1; if (error) { if (error_age) alert("please fill in the age field properly"); else if (error_dre) alert("please fill in the DRE field properly"); else if (error_psa) alert("please fill in the PSA field properly"); else if (error_fpsa) alert("please fill in the Free PSA field properly"); else if (error_bxs) alert("please fill in the Prev. Bx Sessions field properly"); else if (error_volsmpl) alert("please fill in either Prost. Vol field or Sampl. D field"); else if (error_volsmpl2) alert("please fill in either Prost. Vol field or Sampl. D field, not both"); else if (error_smpld) alert("please fill in Sampl. D field properly"); else if (error_pvol) alert("please fill in Prost. Vol field properly"); } else { var age; var dre; var psa; var freepsa; var prevbx; var prostvol; var smpld; var p,z, kE; age = input_rb_age.getControlText(); psa = input_rb_psa.getControlText(); freepsa = input_rb_fpsa.getControlText(); prevbx = input_rb_pbx.getControlText(); prostvol = input_rb_pvol.getControlText(); smpld = input_rb_smpld.getControlText(); if (combo_rb_dre.getControlText() == "Suspicious") dre = 1; if (combo_rb_dre.getControlText() == "Normal") dre = 0; kE = 2.718281828459045235360287471352; if (smpld == "up to 22") { z = (0.04337257 * age) + (1.00489803 * dre) + (0.03408701 * psa) - (0.06800965 * freepsa) - (0.39847122 * prevbx) - (0.01951768 * prostvol) - 0.47394105; p = 100 * (1 / (1 + Math.pow(kE,-z))); } if (prostvol == "up to 220") { z = (0.04889477 * age) + (1.04009098 * dre) + (0.03372980 * psa) - (0.06700937 * freepsa) - (0.47164745 * prevbx) - (0.22066932 * smpld) - 0.57824062; p = 100 * (1 / (1 + Math.pow(kE,-z))); } p = roundNumber(p,1); result_rb_1.setControlText("Your probability of finding prostate cancer "); result_rb_2.setControlText("during a repeat biopsy is "); result_rb_2b.setControlText(""+p+"%"); result_rb_3.setControlText("Please discuss this probability with your physician."); result_rb_4.setControlText("This percentage needs to be interpreted in context"); result_rb_5.setControlText("of your age, general health and several other"); result_rb_6.setControlText("considerations."); container.element().innerHTML = RBpageResult.join(""); tabs.setSelectedItems([0]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } question_rb_age.onClick = function(){ window.open('/local/files/pcat/glossary/Age_at_biopsy.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_rb_dre.onClick = function(){ window.open('/local/files/pcat/glossary/DRE.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_rb_psa.onClick = function(){ window.open('/local/files/pcat/glossary/PSA.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_rb_fpsa.onClick = function(){ window.open('/local/files/pcat/glossary/Percent_free_PSA.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_rb_pbx.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_rb_pvol.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_rb_smpld.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } input_rb_age.onControlActivated = function(event){ if (input_rb_age.getControlText() == "between 45 and 85") { input_rb_age.setControlText(""); } } input_rb_age.onControlDeactivated = function(event){ if (input_rb_age.getControlText() == "") { input_rb_age.setControlText("between 45 and 85"); } } input_rb_psa.onControlActivated = function(event){ if (input_rb_psa.getControlText() == "up to 50") { input_rb_psa.setControlText(""); } } input_rb_psa.onControlDeactivated = function(event){ if (input_rb_psa.getControlText() == "") { input_rb_psa.setControlText("up to 50"); } } input_rb_fpsa.onControlActivated = function(event){ if (input_rb_fpsa.getControlText() == "up to 100") { input_rb_fpsa.setControlText(""); } } input_rb_fpsa.onControlDeactivated = function(event){ if (input_rb_fpsa.getControlText() == "") { input_rb_fpsa.setControlText("up to 100"); } } input_rb_pbx.onControlActivated = function(event){ if (input_rb_pbx.getControlText() == "between 2 and 7") { input_rb_pbx.setControlText(""); } } input_rb_pbx.onControlDeactivated = function(event){ if (input_rb_pbx.getControlText() == "") { input_rb_pbx.setControlText("between 2 and 7"); } } input_rb_pvol.onControlActivated = function(event){ if (input_rb_pvol.getControlText() == "up to 220") { input_rb_pvol.setControlText(""); } } input_rb_pvol.onControlDeactivated = function(event){ if (input_rb_pvol.getControlText() == "") { input_rb_pvol.setControlText("up to 220"); } } input_rb_smpld.onControlActivated = function(event){ if (input_rb_smpld.getControlText() == "up to 22") { input_rb_smpld.setControlText(""); } } input_rb_smpld.onControlDeactivated = function(event){ if (input_rb_smpld.getControlText() == "") { input_rb_smpld.setControlText("up to 22"); } } // end of RB events //-------------------------------------------------------------- // SB events button_sb_calculate.onClick = function(){ var error = 0; var error_age = 0; var error_fpsa = 0; var error_pvol = 0; var error_bphvol = 0; if ( input_sb_age.getControlText() == "between 40 and 80" || input_sb_age.getControlText() < 40 || input_sb_age.getControlText() > 80 || !isNumeric(input_sb_age.getControlText()) ){ error_age = 1; error = 1; } if ( input_sb_fpsa.getControlText() == "up to 45" || input_sb_fpsa.getControlText() < 0 || input_sb_fpsa.getControlText() > 45 || !isNumeric(input_sb_fpsa.getControlText()) ){ error_fpsa = 1; error = 1; } if ( input_sb_pvol.getControlText() == "between 20 and 220" || input_sb_pvol.getControlText() < 20 || input_sb_pvol.getControlText() > 220 || !isNumeric(input_sb_pvol.getControlText()) ){ error_pvol = 1; error = 1; } if ( input_sb_bphvol.getControlText() == "up to 130" || input_sb_bphvol.getControlText() < 0 || input_sb_bphvol.getControlText() > 130 || !isNumeric(input_sb_bphvol.getControlText()) ){ error_bphvol = 1; error = 1; } if (error) { if (error_age) alert("please fill in the age field properly"); else if (error_fpsa) alert("please fill in the Free PSA field properly"); else if (error_pvol) alert("please fill in Prost. Vol field properly"); else if (error_bphvol) alert("please fill in BPH. Vol field properly"); } else { var age; var freepsa; var prostvol; var bphvol; var p,z, kE; age = input_sb_age.getControlText(); freepsa = input_sb_fpsa.getControlText(); bphvol = input_sb_bphvol.getControlText(); prostvol = input_sb_pvol.getControlText(); kE = 2.718281828459045235360287471352; z = (0.06011152 * age) - (0.07949234 * freepsa) + (0.04101865 * prostvol) - (0.07919255 * bphvol) - 2.49258330; p = 100 * (1 / (1 + Math.pow(kE,-z))); p = roundNumber(p,1); result_sb_1.setControlText("The probability of finding prostate cancer "); result_sb_2.setControlText("during a saturation biopsy is "); result_sb_2b.setControlText(""+p+"%"); result_sb_3.setControlText("Please discuss this probability with your physician."); result_sb_4.setControlText("This percentage needs to be interpreted in context"); result_sb_5.setControlText("of your age, general health and several other"); result_sb_6.setControlText("considerations."); container.element().innerHTML = SBpageResult.join(""); tabs.setSelectedItems([0]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } question_sb_age.onClick = function(){ window.open('/local/files/pcat/glossary/Age_at_biopsy.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_sb_fpsa.onClick = function(){ window.open('/local/files/pcat/glossary/Percent_free_PSA.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_sb_pvol.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_sb_bphvol.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } input_sb_age.onControlActivated = function(event){ if (input_sb_age.getControlText() == "between 40 and 80") { input_sb_age.setControlText(""); } } input_sb_age.onControlDeactivated = function(event){ if (input_sb_age.getControlText() == "") { input_sb_age.setControlText("between 40 and 80"); } } input_sb_fpsa.onControlActivated = function(event){ if (input_sb_fpsa.getControlText() == "up to 45") { input_sb_fpsa.setControlText(""); } } input_sb_fpsa.onControlDeactivated = function(event){ if (input_sb_fpsa.getControlText() == "") { input_sb_fpsa.setControlText("up to 45"); } } input_sb_pvol.onControlActivated = function(event){ if (input_sb_pvol.getControlText() == "between 20 and 220") { input_sb_pvol.setControlText(""); } } input_sb_pvol.onControlDeactivated = function(event){ if (input_sb_pvol.getControlText() == "") { input_sb_pvol.setControlText("between 20 and 220"); } } input_sb_bphvol.onControlActivated = function(event){ if (input_sb_bphvol.getControlText() == "up to 130") { input_sb_bphvol.setControlText(""); } } input_sb_bphvol.onControlDeactivated = function(event){ if (input_sb_bphvol.getControlText() == "") { input_sb_bphvol.setControlText("up to 130"); } } //-------------------------------------------------------------- // INSIG events button_insig_calculate.onClick = function(){ var error = 0; var error_psa = 0; var error_ct = 0; var error_ppc = 0; var error_cs = 0; var error_pribg = 0; var error_secbg = 0; if ( input_insig_psa.getControlText() == "up to 50"|| input_insig_psa.getControlText() < 0 || input_insig_psa.getControlText() > 50 || !isNumeric(input_insig_psa.getControlText()) ){ error_psa = 1; error = 1; } if ( input_insig_ct.getControlText() == "up to 70" || input_insig_ct.getControlText() < 0 || input_insig_ct.getControlText() > 70 || !isNumeric(input_insig_ct.getControlText()) ){ error_ct = 1; error = 1; } if ( input_insig_ppc.getControlText() == "between 12.5 and 100" || input_insig_ppc.getControlText() < 12.5 || input_insig_ppc.getControlText() > 100 || !isNumeric(input_insig_ppc.getControlText()) ){ error_ppc = 1; error = 1; } if (combo_insig_cs.getControlText() == "Select"){ error_cs = 1; error = 1; } if (combo_insig_pribg.getControlText() == "Select"){ error_pribg = 1; error = 1; } if (combo_insig_secbg.getControlText() == "Select"){ error_secbg = 1; error = 1; } if (error) { if (error_psa) alert("please fill in the PSA field properly"); else if (error_cs) alert("please fill in the Clinical Stage field properly"); else if (error_pribg) alert("please fill in the Pri. Bx. Gl field properly"); else if (error_secbg) alert("please fill in the Sec. Bx. Gl field properly"); else if (error_ct) alert("please fill in the Cancer tissue (mm) field properly"); else if (error_ppc) alert("please fill in % + Cores field properly"); } else { //window.location.href = "calc_insig.php?psa=" + input_insig_psa.getControlText() + "&cs=" + combo_insig_cs.getControlText() + "&pribg=" + combo_insig_pribg.getControlText() + "&secbg=" + combo_insig_secbg.getControlText() + "&ct=" + input_insig_ct.getControlText() + "&ppc=" + input_insig_ppc.getControlText() + "&radio=" + radio_insig.getSelectedItems(); var psa; var cs; var pribg; var secbg; var ct; var ppc; var radio; var c_label; var p,z, kE; psa = input_insig_psa.getControlText(); ct = input_insig_ct.getControlText(); ppc = input_insig_ppc.getControlText(); radio = radio_insig.getSelectedItems(); if (radio == 0) { c_label = "insignificant prostate cancer"; radio_insig.setSelectedItems([0]); if (combo_insig_pribg.getControlText() == "2") pribg = 0; if (combo_insig_pribg.getControlText() == "3") pribg = -0.17759; if (combo_insig_pribg.getControlText() == "4") pribg = -6.85195; if (combo_insig_secbg.getControlText() == "2") secbg = 0; if (combo_insig_secbg.getControlText() == "3") secbg = -0.67703; if (combo_insig_secbg.getControlText() == "4") secbg = -2.92992; if (combo_insig_secbg.getControlText() == "5") secbg = -1.04925; if (combo_insig_cs.getControlText() == "T1") cs = 0; if (combo_insig_cs.getControlText() == "T2A") cs = -0.45425; if (combo_insig_cs.getControlText() == "T2B") cs = 0.17469; if (combo_insig_cs.getControlText() == "T2C") cs = 1.32017; if (combo_insig_cs.getControlText() == "T3") cs = 2.19734; z = - (0.09943 * psa) - (0.32956 * ct) - (0.05521 * ppc) + pribg + secbg + cs + 1.49285; } if (radio == 1) { c_label = "meaningful prostate cancer >0.5 cc"; radio_insig.setSelectedItems([1]); if (combo_insig_pribg.getControlText() == "2") pribg = 0; if (combo_insig_pribg.getControlText() == "3") pribg = 0.02765; if (combo_insig_pribg.getControlText() == "4") pribg = 6.93932; if (combo_insig_secbg.getControlText() == "2") secbg = 0; if (combo_insig_secbg.getControlText() == "3") secbg = 0.51451; if (combo_insig_secbg.getControlText() == "4") secbg = 1.79698; if (combo_insig_secbg.getControlText() == "5") secbg = 0.68623; if (combo_insig_cs.getControlText() == "T1") cs = 0; if (combo_insig_cs.getControlText() == "T2A") cs = 0.51112; if (combo_insig_cs.getControlText() == "T2B") cs = 0.05379; if (combo_insig_cs.getControlText() == "T2C") cs = -1.18277; if (combo_insig_cs.getControlText() == "T3") cs = -1.95859; z = + (0.09725 * psa) + (0.28493 * ct) + (0.05949 * ppc) + pribg + secbg + cs - 1.30842; } if (radio == 2) { c_label = "meaningful prostate cancer >1.0 cc"; radio_insig.setSelectedItems([2]); if (combo_insig_pribg.getControlText() == "2") pribg = 0; if (combo_insig_pribg.getControlText() == "3") pribg = -0.27829; if (combo_insig_pribg.getControlText() == "4") pribg = -0.16070; if (combo_insig_secbg.getControlText() == "2") secbg = 0; if (combo_insig_secbg.getControlText() == "3") secbg = -0.31675; if (combo_insig_secbg.getControlText() == "4") secbg = 0.11459; if (combo_insig_secbg.getControlText() == "5") secbg = 5.40152; if (combo_insig_cs.getControlText() == "T1") cs = 0; if (combo_insig_cs.getControlText() == "T2A") cs = 0.33086; if (combo_insig_cs.getControlText() == "T2B") cs = 0.27690; if (combo_insig_cs.getControlText() == "T2C") cs = -1.22432; if (combo_insig_cs.getControlText() == "T3") cs = -1.80861; z = + (0.12827 * psa) + (0.21219 * ct) + (0.05066 * ppc) + pribg + secbg + cs - 0.93113; } if (radio == 3) { c_label = "meaningful prostate cancer >2.0 cc"; radio_insig.setSelectedItems([3]); if (combo_insig_pribg.getControlText() == "2") pribg = 0; if (combo_insig_pribg.getControlText() == "3") pribg = 0.09782; if (combo_insig_pribg.getControlText() == "4") pribg = 0.27303; if (combo_insig_secbg.getControlText() == "2") secbg = 0; if (combo_insig_secbg.getControlText() == "3") secbg =0.67758; if (combo_insig_secbg.getControlText() == "4") secbg = 0.03964; if (combo_insig_secbg.getControlText() == "5") secbg = 6.24452; if (combo_insig_cs.getControlText() == "T1") cs = 0; if (combo_insig_cs.getControlText() == "T2A") cs = 0.18334; if (combo_insig_cs.getControlText() == "T2B") cs = 0.64859; if (combo_insig_cs.getControlText() == "T2C") cs = -0.89448; if (combo_insig_cs.getControlText() == "T3") cs = -0.86074; z = + (0.16386 * psa) + (0.07631 * ct) + (0.03051 * ppc) + pribg + secbg + cs - 1.57516; } kE = 2.718281828459045235360287471352; p = 100 * (1 / (1 + Math.pow(kE,-z))); p = roundNumber(p,1); result_insig_1.setControlText("Your probability of having "); result_insig_2.setControlText(c_label + " is "); result_insig_2b.setControlText("" + p + "%"); result_insig_3.setControlText("Please discuss this probability with your physician."); result_insig_4.setControlText("This percentage needs to be interpreted in context"); result_insig_5.setControlText(" of your age, general health and several other"); result_insig_6.setControlText(" considerations."); container.element().innerHTML = INSIGpageResult.join(""); tabs.setSelectedItems([2]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } question_insig_psa.onClick = function(){ window.open('/local/files/pcat/glossary/PSA.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_insig_cs.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_insig_pribg.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_insig_secbg.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_insig_ct.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_insig_ppc.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } input_insig_psa.onControlActivated = function(event){ if (input_insig_psa.getControlText() == "up to 50") { input_insig_psa.setControlText(""); } } input_insig_psa.onControlDeactivated = function(event){ if (input_insig_psa.getControlText() == "") { input_insig_psa.setControlText("up to 50"); } } input_insig_ct.onControlActivated = function(event){ if (input_insig_ct.getControlText() == "up to 70") { input_insig_ct.setControlText(""); } } input_insig_ct.onControlDeactivated = function(event){ if (input_insig_ct.getControlText() == "") { input_insig_ct.setControlText("up to 70"); } } input_insig_ppc.onControlActivated = function(event){ if (input_insig_ppc.getControlText() == "between 12.5 and 100") { input_insig_ppc.setControlText(""); } } input_insig_ppc.onControlDeactivated = function(event){ if (input_insig_ppc.getControlText() == "") { input_insig_ppc.setControlText("between 12.5 and 100"); } } // end of INSIG events //-------------------------------------------------------------- // TZPZ events button_tzpz_calculate.onClick = function(){ var error = 0; var error_psa = 0; var error_bgs = 0; var error_cmo = 0; var error_cb = 0; var error_cvc = 0; if ( input_tzpz_psa.getControlText() == "up to 80" || input_tzpz_psa.getControlText() < 0 || input_tzpz_psa.getControlText() > 80 || !isNumeric(input_tzpz_psa.getControlText()) ){ error_psa = 1; error = 1; } if ( input_tzpz_cvc.getControlText() == "up to 90" || input_tzpz_cvc.getControlText() < 0 || input_tzpz_cvc.getControlText() > 90 || !isNumeric(input_tzpz_cvc.getControlText()) ){ error_cvc = 1; error = 1; } if (combo_tzpz_bgs.getControlText() == "Select"){ error_bgs = 1; error = 1; } if (combo_tzpz_cmo.getControlText() == "Select"){ error_cmo = 1; error = 1; } if (combo_tzpz_cb.getControlText() == "Select"){ error_cb = 1; error = 1; } if (error) { if (error_psa) alert("please fill in the PSA field properly"); else if (error_bgs) alert("please fill in Bx. Gleason sum field properly"); else if (error_cmo) alert("please fill in # + Cores Mid only field properly"); else if (error_cb) alert("please fill in # + Cores Base field properly"); else if (error_cvc) alert("please fill in % Ca Volume / Cores field properly"); } else { var psa; var bgs; var cmo; var cb; var cvc; var p,z, kE; psa = input_tzpz_psa.getControlText(); cvc = input_tzpz_cvc.getControlText(); cmo = combo_tzpz_cmo.getControlText(); cb = combo_tzpz_cb.getControlText(); if (combo_tzpz_bgs.getControlText() == "4 or 5") bgs = 0; if (combo_tzpz_bgs.getControlText() == "6") bgs = -1.80140552; if (combo_tzpz_bgs.getControlText() == "7 (3 + 4)") bgs = -1.60910362; if (combo_tzpz_bgs.getControlText() == "7 (4 + 3)") bgs = -2.10102085; if (combo_tzpz_bgs.getControlText() == "8+") bgs = -2.80120490; kE = 2.718281828459045235360287471352; z = (0.09519106 * psa) + bgs - (1.40357614 * cmo) - (0.98239301 * cb) - (0.04770012 * cvc) - 0.09698167; p = 100 * (1 / (1 + Math.pow(kE,-z))); p = roundNumber(p,1); result_tzpz_1.setControlText("The probability that your tumour is in the"); result_tzpz_2.setControlText("transition zone is "); result_tzpz_2b.setControlText("" + p + "%"); result_tzpz_3.setControlText("Please discuss this probability with your physician."); result_tzpz_4.setControlText("This percentage needs to be interpreted in context"); result_tzpz_5.setControlText(" of your age, general health and several other"); result_tzpz_6.setControlText(" considerations."); container.element().innerHTML = TZPZpageResult.join(""); tabs.setSelectedItems([2]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } question_tzpz_psa.onClick = function(){ window.open('/local/files/pcat/glossary/PSA.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_tzpz_bgs.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_tzpz_cmo.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_tzpz_cb.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_tzpz_cvc.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } input_tzpz_psa.onControlActivated = function(event){ if (input_tzpz_psa.getControlText() == "up to 80") { input_tzpz_psa.setControlText(""); } } input_tzpz_psa.onControlDeactivated = function(event){ if (input_tzpz_psa.getControlText() == "") { input_tzpz_psa.setControlText("up to 80"); } } input_tzpz_cvc.onControlActivated = function(event){ if (input_tzpz_cvc.getControlText() == "up to 90") { input_tzpz_cvc.setControlText(""); } } input_tzpz_cvc.onControlDeactivated = function(event){ if (input_tzpz_cvc.getControlText() == "") { input_tzpz_cvc.setControlText("up to 90"); } } //-------------------------------------------------------------- // gleason sum upgrading events button_gsu_calculate.onClick = function(){ var error = 0; var error_psa = 0; var error_cs = 0; var error_pribg = 0; var error_secbg = 0; if ( input_gsu_psa.getControlText() == "up to 120"|| input_gsu_psa.getControlText() < 0 || input_gsu_psa.getControlText() > 120 || !isNumeric(input_gsu_psa.getControlText()) ){ error_psa = 1; error = 1; } if (combo_gsu_cs.getControlText() == "Select"){ error_cs = 1; error = 1; } if (combo_gsu_pribg.getControlText() == "Select"){ error_pribg = 1; error = 1; } if (combo_gsu_secbg.getControlText() == "Select"){ error_secbg = 1; error = 1; } if (error) { if (error_psa) alert("please fill in the PSA field properly"); else if (error_cs) alert("please fill in the Clinical Stage field properly"); else if (error_pribg) alert("please fill in the Pri. Bx. Gl field properly"); else if (error_secbg) alert("please fill in the Sec. Bx. Gl field properly"); } else { var psa; var cs; var pribg; var secbg; var p,z, kE; psa = input_gsu_psa.getControlText(); if (combo_gsu_pribg.getControlText() == "1 ~ 2") pribg = 0; if (combo_gsu_pribg.getControlText() == "3") pribg = -1.75909187; if (combo_gsu_pribg.getControlText() == "4 ~ 5") pribg = -3.73810052; if (combo_gsu_secbg.getControlText() == "1 ~ 2") secbg = 0; if (combo_gsu_secbg.getControlText() == "3") secbg = -1.23190822; if (combo_gsu_secbg.getControlText() == "4 ~ 5") secbg = -4.44965261; if (combo_gsu_cs.getControlText() == "T1C") cs = 0; if (combo_gsu_cs.getControlText() == "T2A") cs = 0.49024674; if (combo_gsu_cs.getControlText() == "T2B") cs = 0.85812447; if (combo_gsu_cs.getControlText() == "T2C") cs = 0.69658742; if (combo_gsu_cs.getControlText() == "T3") cs = 0.43080512; kE = 2.718281828459045235360287471352; z = + (0.02940016 * psa) + cs + pribg + secbg + 2.01316871; p = 100 * (1 / (1 + Math.pow(kE,-z))); p = roundNumber(p,1); result_gsu_1.setControlText("Your probability of having Gleason sum"); result_gsu_2.setControlText("upgrading is "); result_gsu_2b.setControlText("" + p + "%"); result_gsu_3.setControlText("Please discuss this probability with your physician."); result_gsu_4.setControlText("This percentage needs to be interpreted in context"); result_gsu_5.setControlText(" of your age, general health and several other"); result_gsu_6.setControlText(" considerations."); container.element().innerHTML = GSUpageResult.join(""); tabs.setSelectedItems([1]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } question_gsu_psa.onClick = function(){ alert("blah"); window.open('/local/files/pcat/glossary/PSA.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_gsu_cs.onClick = function(){ alert("blah"); window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_gsu_pribg.onClick = function(){ alert("blah"); window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_gsu_secbg.onClick = function(){ alert("blah"); window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } input_gsu_psa.onControlActivated = function(event){ if (input_gsu_psa.getControlText() == "up to 120") { input_gsu_psa.setControlText(""); } } input_gsu_psa.onControlDeactivated = function(event){ if (input_gsu_psa.getControlText() == "") { input_gsu_psa.setControlText("up to 120"); } } // end of gleason sum upgrading events //-------------------------------------------------------------- // ECE events button_ece_calculate.onClick = function(){ var error = 0; var error_cs = 0; var error_bgs = 0; var error_ppc = 0; var error_pc = 0; var error_psa = 0; if ( input_ece_psa.getControlText() == "up to 80"|| input_ece_psa.getControlText() < 0 || input_ece_psa.getControlText() > 80 || !isNumeric(input_ece_psa.getControlText()) ){ error_psa = 1; error = 1; } if ( input_ece_ppc.getControlText() == "up to 100"|| input_ece_ppc.getControlText() < 0 || input_ece_ppc.getControlText() > 100 || !isNumeric(input_ece_ppc.getControlText()) ){ error_ppc = 1; error = 1; } if ( input_ece_pc.getControlText() == "up to 100"|| input_ece_pc.getControlText() < 0 || input_ece_pc.getControlText() > 100 || !isNumeric(input_ece_pc.getControlText()) ){ error_pc = 1; error = 1; } if (combo_ece_cs.getControlText() == "Select"){ error_cs = 1; error = 1; } if (combo_ece_bgs.getControlText() == "Select"){ error_bgs = 1; error = 1; } if (error) { if (error_psa) alert("please fill in the PPSA field properly"); else if (error_cs) alert("please fill in the Clinical Stage field properly"); else if (error_bgs) alert("please fill in the Bx. Gleason sum field properly"); else if (error_ppc) alert("please fill in the % + Cores field properly"); else if (error_pc) alert("please fill in the % Cancer field properly"); } else { var psa; var cs; var bgs; var ppc; var pc; var p,z, kE; psa = input_ece_psa.getControlText(); pc = input_ece_pc.getControlText(); ppc = input_ece_ppc.getControlText(); if (combo_ece_bgs.getControlText() == "0") bgs = 0; if (combo_ece_bgs.getControlText() == "4 or 5") bgs = -0.67268947; if (combo_ece_bgs.getControlText() == "6") bgs = 0.10406123; if (combo_ece_bgs.getControlText() == "7 (3 + 4)") bgs = 1.13404358; if (combo_ece_bgs.getControlText() == "7 (4 + 3)") bgs = 1.26818981; if (combo_ece_bgs.getControlText() == "8 or 9") bgs = 0.80463625; if (combo_ece_cs.getControlText() == "T1C") cs = 0; if (combo_ece_cs.getControlText() == "T2A") cs = 0.95120051; if (combo_ece_cs.getControlText() == "T2B") cs = 3.88165367; if (combo_ece_cs.getControlText() == "T2C") cs = 1.97360182; if (combo_ece_cs.getControlText() == "T3") cs = 1.51289427; kE = 2.718281828459045235360287471352; z = (0.05715431 * psa) + bgs + cs + (0.00138832 * ppc) + (0.02150559 * pc) - 3.33032634; p = 100 * (1 / (1 + Math.pow(kE,-z))); p = roundNumber(p,1); result_ece_1.setControlText("The probability that your cancer has spread beyond"); result_ece_2.setControlText("the confines of the prostate is"); result_ece_2b.setControlText("" + p + "%"); result_ece_3.setControlText("Please discuss this probability with your physician."); result_ece_4.setControlText("This percentage needs to be interpreted in context"); result_ece_5.setControlText(" of your age, general health and several other"); result_ece_6.setControlText(" considerations."); container.element().innerHTML = ECEpageResult.join(""); tabs.setSelectedItems([1]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } question_ece_psa.onClick = function(){ window.open('/local/files/pcat/glossary/PSA.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_ece_cs.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_ece_bgs.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_ece_ppc.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_ece_pc.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } input_ece_psa.onControlActivated = function(event){ if (input_ece_psa.getControlText() == "up to 80") { input_ece_psa.setControlText(""); } } input_ece_psa.onControlDeactivated = function(event){ if (input_ece_psa.getControlText() == "") { input_ece_psa.setControlText("up to 80"); } } input_ece_ppc.onControlActivated = function(event){ if (input_ece_ppc.getControlText() == "up to 100") { input_ece_ppc.setControlText(""); } } input_ece_ppc.onControlDeactivated = function(event){ if (input_ece_ppc.getControlText() == "") { input_ece_ppc.setControlText("up to 100"); } } input_ece_pc.onControlActivated = function(event){ if (input_ece_pc.getControlText() == "up to 100") { input_ece_pc.setControlText(""); } } input_ece_pc.onControlDeactivated = function(event){ if (input_ece_pc.getControlText() == "") { input_ece_pc.setControlText("up to 100"); } } // end of ECE events //-------------------------------------------------------------- // LOCAL REC events button_loc_calculate.onClick = function(){ var error = 0; var error_pts = 0; var error_psm = 0; var error_pgs = 0; var error_lnd = 0; var error_adj = 0; if (combo_loc_pts.getControlText() == "Select"){ error_pts = 1; error = 1; } if (combo_loc_psm.getControlText() == "Select"){ error_psm = 1; error = 1; } if (combo_loc_pgs.getControlText() == "Select"){ error_pgs = 1; error = 1; } if (combo_loc_lnd.getControlText() == "Select"){ error_lnd = 1; error = 1; } if (combo_loc_adj.getControlText() == "Select"){ error_adj = 1; error = 1; } if (error) { if (error_pts) alert("please fill in the Path T stage field properly"); else if (error_psm) alert("please fill in + SM field properly"); else if (error_pgs) alert("please fill in Path Gl. sum field properly"); else if (error_lnd) alert("please fill in LN Dissection field properly"); else if (error_adj) alert("please fill in Adjuvant XRT field properly"); } else { var pts; var psm; var pgs; var lnd; var adj; var p5y, p10y, p15y, p20y, z, kE; if (combo_loc_pts.getControlText() == "T2b/c") pts = -0.21265001695048; if (combo_loc_pts.getControlText() == "T2a") pts = 0; if (combo_loc_pts.getControlText() == "T3") pts = 0.53389470410897; if (combo_loc_psm.getControlText() == "Yes") psm = 0.50531876689382; if (combo_loc_psm.getControlText() == "No") psm = 0; if (combo_loc_pgs.getControlText() == "2 - 5") pgs = 0; if (combo_loc_pgs.getControlText() == "6") pgs = 1.65136777602632; if (combo_loc_pgs.getControlText() == "7") pgs = 0.90302583544791; if (combo_loc_pgs.getControlText() == "8 - 10") pgs = 2.10509004906015; if (combo_loc_lnd.getControlText() == "Yes") lnd = -0.51322385026542; if (combo_loc_lnd.getControlText() == "No") lnd = 0; if (combo_loc_adj.getControlText() == "Yes") adj = -1.27790265948538; if (combo_loc_adj.getControlText() == "No") adj = 0; kE = 2.718281828459045235360287471352; z = pts + psm + pgs + lnd + adj - 0.96925819242613; p5y = 100 * Math.pow(kE, Math.pow(kE, z - 0.4282914988575) * Math.log(0.9527533239802) ); p10y = 100 * Math.pow(kE, Math.pow(kE, z - 0.4136022881803) * Math.log(0.9122689612292) ); p15y = 100 * Math.pow(kE, Math.pow(kE, z - 0.4111214326715) * Math.log(0.8963814840358) ); p20y = 100 * Math.pow(kE, Math.pow(kE, z - 0.4242354585820) * Math.log(0.8779834001633) ); p5y = roundNumber(p5y,1); p10y = roundNumber(p10y,1); p15y = roundNumber(p15y,1); p20y = roundNumber(p20y,1); result_loc_1.setControlText("Your probability of NOT having"); result_loc_2.setControlText("local recurrence after radical prostatectomy is"); result_loc_3.setControlText("at 5 years   = " + p5y + "%"); result_loc_4.setControlText("at 10 years = " + p10y + "%"); result_loc_5.setControlText("at 15 years = " + p15y + "%"); result_loc_6.setControlText("at 20 years = " + p20y + "%"); result_loc_7.setControlText("Please discuss this probability with your physician."); result_loc_8.setControlText("This percentage needs to be interpreted in context"); result_loc_9.setControlText("of your age, general health and several other"); result_loc_10.setControlText("considerations."); container.element().innerHTML = LOCpageResult.join(""); tabs.setSelectedItems([3]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } question_loc_pts.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_loc_psm.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_loc_pgs.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_loc_lnd.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_loc_adj.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } // end of Local Recurrence //-------------------------------------------------------------- // DISTANT REC events button_dis_calculate.onClick = function(){ var error = 0; var error_pts = 0; var error_pgs = 0; var error_cor = 0; var error_adj = 0; if (combo_dis_pts.getControlText() == "Select"){ error_pts = 1; error = 1; } if (combo_dis_pgs.getControlText() == "Select"){ error_pgs = 1; error = 1; } if (combo_dis_cor.getControlText() == "Select"){ error_cor = 1; error = 1; } if (combo_dis_adj.getControlText() == "Select"){ error_adj = 1; error = 1; } if (error) { if (error_pts) alert("please fill in the Path T stage field properly"); else if (error_pgs) alert("please fill in Path Gl. sum field properly"); else if (error_cor) alert("please fill in Cormobidity field properly"); else if (error_adj) alert("please fill in Adjuvant XRT field properly"); } else { var pts; var pgs; var cor; var adj; var p5y, p10y, p15y, p20y, z, kE; if (combo_dis_pts.getControlText() == "T2b/c") pts = 0.13826729885457; if (combo_dis_pts.getControlText() == "T2a") pts = 0; if (combo_dis_pts.getControlText() == "T3") pts = 0.81019265035119; if (combo_dis_pgs.getControlText() == "2 - 5") pgs = 0; if (combo_dis_pgs.getControlText() == "6") pgs = 1.24749375515049; if (combo_dis_pgs.getControlText() == "7") pgs = 1.23187348542196; if (combo_dis_pgs.getControlText() == "8 - 10") pgs = 1.94219683078794; if (combo_dis_cor.getControlText() == "0") cor = 0; if (combo_dis_cor.getControlText() == "1+") cor = -1.0831008077362; if (combo_dis_adj.getControlText() == "Yes") adj = 0.67189352135731; if (combo_dis_adj.getControlText() == "No") adj = 0; kE = 2.718281828459045235360287471352; z = pts + pgs + cor + adj - 1.35654713930177; p5y = 100 * Math.pow(kE, Math.pow(kE, z - 0.4017061472304) * Math.log(0.9594600133537) ); p10y = 100 * Math.pow(kE, Math.pow(kE, z - 0.3673716434017) * Math.log(0.9054296719078) ); p15y = 100 * Math.pow(kE, Math.pow(kE, z - 0.3108802570177) * Math.log(0.8483076036185) ); p20y = 100 * Math.pow(kE, Math.pow(kE, z - 0.2899121311401) * Math.log(0.8050509006682) ); p5y = roundNumber(p5y,1); p10y = roundNumber(p10y,1); p15y = roundNumber(p15y,1); p20y = roundNumber(p20y,1); result_dis_1.setControlText("Your probability of NOT having distant recurrence"); result_dis_2.setControlText("after radical prostatectomy is"); result_dis_3.setControlText("at 5 years   = "+p5y+"%"); result_dis_4.setControlText("at 10 years = "+p10y+"%"); result_dis_5.setControlText("at 15 years = "+p15y+"%"); result_dis_6.setControlText("at 20 years = "+p20y+"%"); result_dis_7.setControlText("Please discuss this probability with your physician."); result_dis_8.setControlText("This percentage needs to be interpreted in context"); result_dis_9.setControlText("of your age, general health and several other"); result_dis_10.setControlText("considerations."); container.element().innerHTML = DISpageResult.join(""); tabs.setSelectedItems([3]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } question_dis_pts.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_dis_pgs.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_dis_cor.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_dis_adj.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } // end of distant Recurrence //-------------------------------------------------------------- // PCA SS events button_pcass_calculate.onClick = function(){ var error = 0; var error_age = 0; var error_pts = 0; var error_pgs = 0; var error_lnd = 0; var error_xrt = 0; if (combo_pcass_age.getControlText() == "Select"){ error_age = 1; error = 1; } if (combo_pcass_pts.getControlText() == "Select"){ error_pts = 1; error = 1; } if (combo_pcass_pgs.getControlText() == "Select"){ error_pgs = 1; error = 1; } if (combo_pcass_lnd.getControlText() == "Select"){ error_lnd = 1; error = 1; } if (combo_pcass_xrt.getControlText() == "Select"){ error_xrt = 1; error = 1; } if (error) { if (error_age) alert("please fill in Age at biopsy field properly"); else if (error_pts) alert("please fill in the Path T stage field properly"); else if (error_pgs) alert("please fill in Path Gl. sum field properly"); else if (error_lnd) alert("please fill in LN Dissection field properly"); else if (error_xrt) alert("please fill in XRT field properly"); } else { var age; var pts; var pgs; var lnd; var xrt; var p5y, p10y, p15y, p20y, z, kE; if (combo_pcass_age.getControlText() == "< or equal to 64.6") age = 0; if (combo_pcass_age.getControlText() == "> 64.6") age = -0.86941469372128; if (combo_pcass_pts.getControlText() == "T2b/c") pts = 0.12389399574710; if (combo_pcass_pts.getControlText() == "T2a") pts = 0; if (combo_pcass_pts.getControlText() == "T3") pts = 1.00137727534106; if (combo_pcass_pgs.getControlText() == "2 - 5") pgs = 0; if (combo_pcass_pgs.getControlText() == "6") pgs = 0.85898774647245; if (combo_pcass_pgs.getControlText() == "7") pgs = 1.09507673260222; if (combo_pcass_pgs.getControlText() == "8 - 10") pgs = 2.28655312152840; if (combo_pcass_lnd.getControlText() == "Yes") lnd = -0.40425878795810 ; if (combo_pcass_lnd.getControlText() == "No") lnd= 0; if (combo_pcass_xrt.getControlText() == "Yes") xrt = 1.16551019283589; if (combo_pcass_xrt.getControlText() == "No") xrt = 0; kE = 2.718281828459045235360287471352; z = pts + age + pgs + lnd + xrt - 0.96040093464059; p5y =100 * Math.pow(kE, Math.pow(kE, z - 0.8082111411259) * Math.log(0.9898029995373) ); p10y =100 * Math.pow(kE, Math.pow(kE, z - 0.7428804134374) * Math.log(0.9550082348093) ); p15y =100 * Math.pow(kE, Math.pow(kE, z - 0.7387986000491) * Math.log(0.9090022006615) ); p20y =100 * Math.pow(kE, Math.pow(kE, z - 0.7576736113857) * Math.log(0.8571339710996) ); p5y = roundNumber(p5y,1); p10y = roundNumber(p10y,1); p15y = roundNumber(p15y,1); p20y = roundNumber(p20y,1); result_pcass_1.setControlText("Your probability of NOT dying of prostate cancer"); result_pcass_2.setControlText("after a radical prostatectomy is"); result_pcass_3.setControlText("at 5 years   = "+p5y+"%"); result_pcass_4.setControlText("at 10 years = "+p10y+"%"); result_pcass_5.setControlText("at 15 years = "+p15y+"%"); result_pcass_6.setControlText("at 20 years = "+p20y+"%"); result_pcass_7.setControlText("Please discuss this probability with your physician."); result_pcass_8.setControlText("This percentage needs to be interpreted in context"); result_pcass_9.setControlText("of your age, general health and several other"); result_pcass_10.setControlText("considerations."); container.element().innerHTML = PCASSpageResult.join(""); tabs.setSelectedItems([3]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } question_pcass_age.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_pcass_pts.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_pcass_pgs.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_pcass_lnd.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_pcass_xrt.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } // end of PCA SS //-------------------------------------------------------------- // AIPC events button_aipc_calculate.onClick = function(){ var error = 0; var error_psaadt = 0; var error_psadt = 0; var error_npsaadt = 0; var error_tinme = 0; if ( input_aipc_psaadt.getControlText() == "up to 2400"|| input_aipc_psaadt.getControlText() < 0 || input_aipc_psaadt.getControlText() > 2400 || !isNumeric(input_aipc_psaadt.getControlText()) ){ error_psaadt = 1; error = 1; } if ( input_aipc_psadt.getControlText() == "up to 30"|| input_aipc_psadt.getControlText() < 0 || input_aipc_psadt.getControlText() > 30 || !isNumeric(input_aipc_psadt.getControlText()) ){ error_psadt = 1; error = 1; } if ( input_aipc_npsaadt.getControlText() == "up to 110"|| input_aipc_npsaadt.getControlText() < 0 || input_aipc_npsaadt.getControlText() > 110 || !isNumeric(input_aipc_npsaadt.getControlText()) ){ error_npsaadt = 1; error = 1; } if ( input_aipc_time.getControlText() == "up to 90"|| input_aipc_time.getControlText() < 0 || input_aipc_time.getControlText() > 90 || !isNumeric(input_aipc_time.getControlText()) ){ error_time = 1; error = 1; } if (error) { if (error_psaadt) alert("please fill in the PSA at ADT init. field properly"); else if (error_psadt) alert("please fill in the PSA doubling time field properly"); else if (error_npsaadt) alert("please fill in the Nadir PSA on ADT field properly"); else if (error_time) alert("please fill in the Time ADT >= AIPC(M) field properly"); } else { var psaadt = input_aipc_psaadt.getControlText(); var psadt = input_aipc_psadt.getControlText(); var npsaadt = input_aipc_npsaadt.getControlText(); var time = input_aipc_time.getControlText(); var pk1 = 8.247; var pk2 = 54.35; var pk3 = 356.62; var pkd = Math.pow((pk3 - pk1),(2/3)); var psaadt_prime = Math.pow(Math.max(((psaadt - pk1) / pkd), 0), 3) + (pk2 - pk1) / (pk3 - pk2) * Math.pow(Math.max(((psaadt - pk3) / pkd),0), 3) + (pk1 - pk3) / (pk3 - pk2) * Math.pow(Math.max(((psaadt - pk2) / pkd), 0), 3); var tk1 = 7.496667; var tk2 = 18.1; var tk3 = 40.55; var tkd = Math.pow((tk3 - tk1),(2/3)); var time_prime = Math.pow(Math.max(((time - tk1) / tkd), 0), 3) + (tk2 - tk1) / (tk3 - tk2) * Math.pow(Math.max(((time - tk3) / tkd), 0), 3) + (tk1 - tk3) / (tk3 - tk2) * Math.pow(Math.max(((time - tk2) / tkd), 0), 3); var kE = 2.718281828459045235360287471352; var z = 2.93383019486184 + (psaadt * 0.00403885813034) + (psaadt_prime * (-0.01107482460102)) + (psadt * (-0.22864165982598)) + (npsaadt * 0.01753418423331) + (time * (-0.09668625059793)) + (time_prime * 0.11431915737335); var p1y =100 * Math.pow(kE, Math.pow(kE, z - 0.8161442346207) * Math.log(0.8493316129764) ); var p2y =100 * Math.pow(kE, Math.pow(kE, z - 0.5085346438741) * Math.log(0.7237977272461) ); var p3y =100 * Math.pow(kE, Math.pow(kE, z - 0.3424189146943) * Math.log(0.6479944353772) ); var p4y =100 * Math.pow(kE, Math.pow(kE, z - 0.1808011324429) * Math.log(0.5511230226183) ); var p5y =100 * Math.pow(kE, Math.pow(kE, z + 0.0182228100478) * Math.log(0.4380005861031) ); p1y = roundNumber(p1y,1); p2y = roundNumber(p2y,1); p3y = roundNumber(p3y,1); p4y = roundNumber(p4y,1); p5y = roundNumber(p5y,1); result_aipc_1.setControlText("The probabilities of NOT dying at the following"); result_aipc_2.setControlText("points in time after the diagnosis of"); result_aipc_3.setControlText ("hormone refractory prostate cancer are:"); result_aipc_4.setControlText("12 months after diagnosis = "+p1y+"%"); result_aipc_5.setControlText("24 months after diagnosis = "+p2y+"%"); result_aipc_6.setControlText("36 months after diagnosis = "+p3y+"%"); result_aipc_7.setControlText("48 months after diagnosis= "+p4y+"%"); result_aipc_8.setControlText("60 months after diagnosis= "+p5y+"%"); result_aipc_9.setControlText("Please discuss these probabilities with your physician."); result_aipc_10.setControlText("Thess percentages need to be interpreted in context"); result_aipc_11.setControlText("of your age, general health and several other"); result_aipc_12.setControlText("considerations."); container.element().innerHTML = AIPCpageResult.join(""); tabs.setSelectedItems([5]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } question_aipc_psaadt.onClick = function(){ window.open('/local/files/pcat/glossary/PSA.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_aipc_psadt.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_aipc_npsaadt.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_aipc_time.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } input_aipc_psaadt.onControlActivated = function(event){ if (input_aipc_psaadt.getControlText() == "up to 2400") { input_aipc_psaadt.setControlText(""); } } input_aipc_psaadt.onControlDeactivated = function(event){ if (input_aipc_psaadt.getControlText() == "") { input_aipc_psaadt.setControlText("up to 2400"); } } input_aipc_psadt.onControlActivated = function(event){ if (input_aipc_psadt.getControlText() == "up to 30") { input_aipc_psadt.setControlText(""); } } input_aipc_psadt.onControlDeactivated = function(event){ if (input_aipc_psadt.getControlText() == "") { input_aipc_psadt.setControlText("up to 30"); } } input_aipc_npsaadt.onControlActivated = function(event){ if (input_aipc_npsaadt.getControlText() == "up to 110") { input_aipc_npsaadt.setControlText(""); } } input_aipc_npsaadt.onControlDeactivated = function(event){ if (input_aipc_npsaadt.getControlText() == "") { input_aipc_npsaadt.setControlText("up to 110"); } } input_aipc_time.onControlActivated = function(event){ if (input_aipc_time.getControlText() == "up to 90") { input_aipc_time.setControlText(""); } } input_aipc_time.onControlDeactivated = function(event){ if (input_aipc_time.getControlText() == "") { input_aipc_time.setControlText("up to 90"); } } // end of AIPC events //-------------------------------------------------------------- //-------------------------------------------------------------- // PSA REC (reduce) events button_psa_calculate.onClick = function(){ var error = 0; var error_pts = 0; var error_psm = 0; var error_pgs = 0; var error_pt = 0; var error_adj = 0; if (combo_psa_pts.getControlText() == "Select"){ error_pts = 1; error = 1; } if (combo_psa_psm.getControlText() == "Select"){ error_psm = 1; error = 1; } if (combo_psa_pgs.getControlText() == "Select"){ error_pgs = 1; error = 1; } if (combo_psa_pt.getControlText() == "Select"){ error_pt = 1; error = 1; } if (combo_psa_adj.getControlText() == "Select"){ error_adj = 1; error = 1; } if (error) { if (error_pts) alert("please fill in the Path T stage field properly"); else if (error_psm) alert("please fill in + SM field properly"); else if (error_pgs) alert("please fill in Path Gl. sum field properly"); else if (error_pt) alert("please fill in Procedure type field properly"); else if (error_adj) alert("please fill in Adjuvant XRT field properly"); } else { var pts; var psm; var pgs; var pt; var adj; var p5y, p10y, p15y, p20y, z, kE; if (combo_psa_pts.getControlText() == "T2b/c") pts = 0.35542880901744; if (combo_psa_pts.getControlText() == "T2a") pts = 0; if (combo_psa_pts.getControlText() == "T3") pts = 0.76461973648260; if (combo_psa_psm.getControlText() == "Yes") psm = 0.54493944278091; if (combo_psa_psm.getControlText() == "No") psm = 0; if (combo_psa_pgs.getControlText() == "2 - 5") pgs = 0; if (combo_psa_pgs.getControlText() == "6") pgs = 0.84126608570529; if (combo_psa_pgs.getControlText() == "7") pgs = 1.39552249085300; if (combo_psa_pgs.getControlText() == "8 - 10") pgs = 1.61353574498900; if (combo_psa_pt.getControlText() == "Perineal") pt = 0; if (combo_psa_pt.getControlText() == "Retropubic") pt = 0.41075439367260; if (combo_psa_adj.getControlText() == "Yes") adj = -0.43589790494138; if (combo_psa_adj.getControlText() == "No") adj = 0; kE = 2.718281828459045235360287471352; z = pts + psm + pgs + pt + adj - 1.62255792871118; p5y = 100 * Math.pow(kE, Math.pow(kE, z + 2.5172604075150) * Math.log(0.9898029995373) ); p10y = 100 * Math.pow(kE, Math.pow(kE, z + 1.8479013968464) * Math.log(0.9550082348093) ); p15y = 100 * Math.pow(kE, Math.pow(kE, z + 1.5670320100118) * Math.log(0.9090022006615) ); p20y = 100 * Math.pow(kE, Math.pow(kE, z + 1.1908998920795) * Math.log(0.8571339710996) ); p5y = roundNumber(p5y,1); p10y = roundNumber(p10y,1); p15y = roundNumber(p15y,1); p20y = roundNumber(p20y,1); result_psa_1.setControlText("Your probability of NOT having a PSA recurrence"); result_psa_2.setControlText("after radical prostatectomy is"); result_psa_3.setControlText("at 5 years  = "+p5y+"%"); result_psa_4.setControlText("at 10 years = "+p10y+"%"); result_psa_5.setControlText("at 15 years = "+p15y+"%"); result_psa_6.setControlText("at 20 years = "+p20y+"%"); result_psa_7.setControlText("Please discuss this probability with your physician."); result_psa_8.setControlText("This percentage needs to be interpreted in context"); result_psa_9.setControlText("of your age, general health and several other"); result_psa_10.setControlText("considerations."); container.element().innerHTML = PSApageResult.join(""); tabs.setSelectedItems([3]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } question_psa_pts.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_psa_psm.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_psa_pgs.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_psa_pt.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_psa_adj.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } // end of PSA Recurrence (reduced) //-------------------------------------------------------------- // META events button_meta_calculate.onClick = function(){ var error = 0; var error_age = 0; var error_pgs = 0; var error_time = 0; var error_adj = 0; if (combo_meta_age.getControlText() == "Select"){ error_age = 1; error = 1; } if (combo_meta_pgs.getControlText() == "Select"){ error_pgs = 1; error = 1; } if (combo_meta_time.getControlText() == "Select"){ error_time = 1; error = 1; } if (combo_meta_adj.getControlText() == "Select"){ error_adj = 1; error = 1; } if (error) { if (error_age) alert("please fill in Age at BCR field properly"); else if (error_pgs) alert("please fill in Path Gl. sum field properly"); else if (error_xrt) alert("please fill in Adjuvant XRT field properly"); else if (error_time) alert("please fill in Time Surg to BCR field properly"); } else { var age; var pgs; var time; var adj; var p5y, p10y, p15y, p20y, z, kE; if (combo_meta_age.getControlText() == "< or equal to 62.4") age = 0; if (combo_meta_age.getControlText() == "between 62.4 and 67.9") age = 0.88894866052600; if (combo_meta_age.getControlText() == "> 67.9") age = -0.91904948914545; if (combo_meta_pgs.getControlText() == "2 - 6") pgs = 0; if (combo_meta_pgs.getControlText() == "7") pgs = 0.70670904635702; if (combo_meta_pgs.getControlText() == "8 - 10") pgs = 1.30055013328041; if (combo_meta_time.getControlText() == "< or equal to 98 months") time = 0; if (combo_meta_time.getControlText() == "> 98 months") time = -0.91924443513307; if (combo_meta_adj.getControlText() == "Yes") adj = 1.54753727307060; if (combo_meta_adj.getControlText() == "No") adj = 0; kE = 2.718281828459045235360287471352; z = age + pgs + time + adj - 0.58253515405702; p2y = 100 * Math.pow(kE, Math.pow(kE, z - 0.5829811193465) * Math.log(0.9128209977258) ); p5y = 100 * Math.pow(kE, Math.pow(kE, z - 0.4707913032542) * Math.log(0.8196650749803) ); p10y = 100 * Math.pow(kE, Math.pow(kE, z - 0.3047375670078) * Math.log(0.7524784392226) ); p2y = roundNumber(p2y,1); p5y = roundNumber(p5y,1); p10y = roundNumber(p10y,1); result_meta_1.setControlText("Your probability of NOT having distant metastases"); result_meta_2.setControlText("after radical prostatectomy and PSA recurrence is"); result_meta_4.setControlText("at 2 years after PSA recurrence= "+p2y+"%"); result_meta_5.setControlText("at 5 years after PSA recurrence= "+p5y+"%"); result_meta_6.setControlText("at 10 years after PSA recurrence= "+p10y+"%"); result_meta_7.setControlText("Please discuss this probability with your"); result_meta_8.setControlText("physician. This percentage needs to be"); result_meta_9.setControlText("interpreted in contextof your age, general"); result_meta_10.setControlText("health and several other considerations."); container.element().innerHTML = METApageResult.join(""); tabs.setSelectedItems([4]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } question_meta_age.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_meta_pgs.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_meta_time.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } question_meta_adj.onClick = function(){ window.open('/local/files/pcat/glossary/.htm','name','height=750, width=550,toolbar=no,directories=no,status=no, menubar=no,scrollbars=yes,left=525,top=70,resizable=yes'); return false; } // end of META //-------------------------------------------------------------- //-------------------------------------------------------------- // EXT B events button_extb_calculate.onClick = function(){ var error = 0; var error_age = 0; var error_dre = 0; var error_psa = 0; var error_fpsa = 0; var error_smpld = 0; if ( input_extb_age.getControlText() == "between 35 and 95" || input_extb_age.getControlText() < 35 || input_extb_age.getControlText() > 95 || !isNumeric(input_extb_age.getControlText()) ){ error_age = 1; error = 1; } if ( input_extb_psa.getControlText() == "up to 50"|| input_extb_psa.getControlText() < 0 || input_extb_psa.getControlText() > 50 || !isNumeric(input_extb_psa.getControlText()) ){ error_psa = 1; error = 1; } if ( input_extb_fpsa.getControlText() == "up to 90" || input_extb_fpsa.getControlText() < 0 || input_extb_fpsa.getControlText() > 90 || !isNumeric(input_extb_fpsa.getControlText()) ){ error_fpsa = 1; error = 1; } if ( input_extb_smpld.getControlText() == "up to 32" || input_extb_smpld.getControlText() < 0 || input_extb_smpld.getControlText() > 32 || !isNumeric(input_extb_smpld.getControlText()) ){ error_smpld = 1; error = 1; } if (combo_extb_dre.getControlText() == "Select"){ error_dre = 1; error = 1; } if (error) { if (error_age) alert("please fill in the age field properly"); else if (error_dre) alert("please fill in the DRE field properly"); else if (error_psa) alert("please fill in the PSA field properly"); else if (error_fpsa) alert("please fill in the Free PSA field properly"); else if (error_smpld) alert("please fill in Sample Density field properly"); } else { var age; var dre; var psa; var freepsa; var smpld; var p,z, kE; age = input_extb_age.getControlText(); psa = input_extb_psa.getControlText(); freepsa = input_extb_fpsa.getControlText(); smpld = input_extb_smpld.getControlText(); if (combo_extb_dre.getControlText() == "Suspicious") dre = 1; if (combo_extb_dre.getControlText() == "Normal") dre = 0; kE = 2.718281828459045235360287471352; z = (0.04860701 * age) + (1.05402953 * dre) + (0.07223122 * psa) - (0.06300559 * freepsa) - (0.17744213 * smpld) - 1.69408031; p = 100 * (1 / (1 + Math.pow(kE,-z))); p = roundNumber(p,1); result_extb_1.setControlText("Your probability of having prostate cancer "); result_extb_2.setControlText("at initial extended biopsy is "); result_extb_2b.setControlText(""+p+"%"); result_extb_3.setControlText("Please discuss this probability with your physician."); result_extb_4.setControlText("This percentage needs to be interpreted in context"); result_extb_5.setControlText("of your age, general health and several other"); result_extb_6.setControlText("considerations."); container.element().innerHTML = EXTBpageResult.join(""); tabs.setSelectedItems([0]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } input_extb_age.onControlActivated = function(event){ if (input_extb_age.getControlText() == "between 35 and 95") { input_extb_age.setControlText(""); } } input_extb_age.onControlDeactivated = function(event){ if (input_extb_age.getControlText() == "") { input_extb_age.setControlText("between 35 and 95"); } } input_extb_psa.onControlActivated = function(event){ if (input_extb_psa.getControlText() == "up to 50") { input_extb_psa.setControlText(""); } } input_extb_psa.onControlDeactivated = function(event){ if (input_extb_psa.getControlText() == "") { input_extb_psa.setControlText("up to 50"); } } input_extb_fpsa.onControlActivated = function(event){ if (input_extb_fpsa.getControlText() == "up to 90") { input_extb_fpsa.setControlText(""); } } input_extb_fpsa.onControlDeactivated = function(event){ if (input_extb_fpsa.getControlText() == "") { input_extb_fpsa.setControlText("up to 90"); } } input_extb_smpld.onControlActivated = function(event){ if (input_extb_smpld.getControlText() == "up to 32") { input_extb_smpld.setControlText(""); } } input_extb_smpld.onControlDeactivated = function(event){ if (input_extb_smpld.getControlText() == "") { input_extb_smpld.setControlText("up to 32"); } } // end of EXT B events //-------------------------------------------------------------- //-------------------------------------------------------------- // MORT 120 events button_mort120_calculate.onClick = function(){ var error = 0; var error_age = 0; var error_cormo = 0; var error_freq = 0; if ( input_mort120_age.getControlText() == "between 35 and 105" || input_mort120_age.getControlText() < 35 || input_mort120_age.getControlText() > 105 || !isNumeric(input_mort120_age.getControlText()) ){ error_age = 1; error = 1; } if (combo_mort120_cormo.getControlText() == "Select"){ error_cormo = 1; error = 1; } if (combo_mort120_freq.getControlText() == "Select"){ error_freq = 1; error = 1; } if (error) { if (error_age) alert("please fill in the age field properly"); else if (error_cormo) alert("please fill in the Cormobidity field properly"); else if (error_freq) alert("please fill in the Bx. Frequency field properly"); } else { var age; var cormo; var freq; var p,z, kE; age = input_mort120_age.getControlText(); if (combo_mort120_cormo.getControlText() == "0") cormo = 0; if (combo_mort120_cormo.getControlText() == "1 - 2") cormo = 0.36090247; if (combo_mort120_cormo.getControlText() == "3 - 4") cormo = 0.78638491; if (combo_mort120_cormo.getControlText() == "5 - 6") cormo = 0.97606376; if (combo_mort120_cormo.getControlText() == "7+") cormo = 1.50752169; if (combo_mort120_freq.getControlText() == "1") freq = 0; if (combo_mort120_freq.getControlText() == "2") freq = -0.68893618; if (combo_mort120_freq.getControlText() == "3+") freq = -0.71251382; kE = 2.718281828459045235360287471352; var k1 = 57; var k2 = 66; var k3 = 72; var k4 = 82; var kd = Math.pow((k4 - k1),(2/3)); var age_prime = Math.pow(Math.max((age - k1)/kd, 0),3) + ( (k3 - k1) * Math.pow(Math.max((age - k4)/kd, 0),3) - (k4 - k1) * (Math.pow(Math.max((age - k3)/kd, 0),3)) )/(k4 - k3); var age_dprime = Math.pow(Math.max((age - k2)/kd, 0),3) + ( (k3 - k2) * Math.pow(Math.max((age - k4)/kd, 0),3) - (k4 - k2) * (Math.pow(Math.max((age - k3)/kd, 0),3)) )/(k4 - k3); z = - 9.54588705 + (age * 0.05574103) + (age_prime * 0.18662372) - (age_dprime * 0.60133524) + cormo + freq; p = 100 * (1 / (1 + Math.pow(kE,-z))); p = roundNumber(p,1); result_mort120_1.setControlText("Your probability of dying (of any cause)"); result_mort120_2.setControlText("within 120 days of a biopsy is "); result_mort120_2b.setControlText(""+p+"%"); result_mort120_3.setControlText("Please discuss this probability with your physician."); result_mort120_4.setControlText("This percentage needs to be interpreted in context"); result_mort120_5.setControlText("of your age, general health and several other"); result_mort120_6.setControlText("considerations."); container.element().innerHTML = MORT120pageResult.join(""); tabs.setSelectedItems([0]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } input_mort120_age.onControlActivated = function(event){ if (input_mort120_age.getControlText() == "between 35 and 105") { input_mort120_age.setControlText(""); } } input_mort120_age.onControlDeactivated = function(event){ if (input_mort120_age.getControlText() == "") { input_mort120_age.setControlText("between 35 and 105"); } } // end of MORT 120 events //-------------------------------------------------------------- // LRM SVI events button_lsvi_calculate.onClick = function(){ var error = 0; var error_psa = 0; var error_cs = 0; var error_gsm = 0; var error_ppc = 0; if ( input_lsvi_psa.getControlText() == "up to 45" || input_lsvi_psa.getControlText() < 0 || input_lsvi_psa.getControlText() > 45 || !isNumeric(input_lsvi_psa.getControlText()) ){ error_psa = 1; error = 1; } if (combo_lsvi_cs.getControlText() == "Select"){ error_cs = 1; error = 1; } if (combo_lsvi_gsm.getControlText() == "Select"){ error_gsm = 1; error = 1; } if (combo_lsvi_ppc.getControlText() == "Select"){ error_ppc = 1; error = 1; } if (error) { if (error_psa) alert("please fill in the PSA field properly"); else if (error_cs) alert("please fill in the Clinical Stage field properly"); else if (error_gsm) alert("please fill in the Gleason Sum field properly"); else if (error_ppc) alert("please fill in the % + Cores field properly"); } else { var psa; var cs; var gsm; var ppc; var p,z, kE; psa = input_lsvi_psa.getControlText(); if (combo_lsvi_cs.getControlText() == "T1c") cs = 0; if (combo_lsvi_cs.getControlText() == "T2") cs = 0.83668658; if (combo_lsvi_cs.getControlText() == "T3") cs = 0.92830462; if (combo_lsvi_gsm.getControlText() == "2 - 5") gsm = 0; if (combo_lsvi_gsm.getControlText() == "6") gsm = 0.53250137; if (combo_lsvi_gsm.getControlText() == "7") gsm = 1.75672090; if (combo_lsvi_gsm.getControlText() == "8 - 10") gsm = 2.23626344; if (combo_lsvi_ppc.getControlText() == "< or equal to 59") ppc = 0; if (combo_lsvi_ppc.getControlText() == "> 59") ppc = 0.93588923; kE = 2.718281828459045235360287471352; z = (0.04917794 * psa) + cs + gsm + ppc - 4.50246266 ; p = 100 * (1 / (1 + Math.pow(kE,-z))); p = roundNumber(p,1); result_lsvi_1.setControlText("The probability that your cancer has"); result_lsvi_2.setControlText("spread into the seminal vesicles is "); result_lsvi_2b.setControlText(""+p+"%"); result_lsvi_3.setControlText("Please discuss this probability with your physician."); result_lsvi_4.setControlText("This percentage needs to be interpreted in context"); result_lsvi_5.setControlText("of your age, general health and several other"); result_lsvi_6.setControlText("considerations."); container.element().innerHTML = LSVIpageResult.join(""); tabs.setSelectedItems([1]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } input_lsvi_psa.onControlActivated = function(event){ if (input_lsvi_psa.getControlText() == "up to 45") { input_lsvi_psa.setControlText(""); } } input_lsvi_psa.onControlDeactivated = function(event){ if (input_lsvi_psa.getControlText() == "") { input_lsvi_psa.setControlText("up to 45"); } } // end of LRM SVI events //-------------------------------------------------------------- // LRM RMV events button_lrmv_calculate.onClick = function(){ var error = 0; var error_psa = 0; var error_cs = 0; var error_gsm = 0; var error_nodes = 0; if ( input_lrmv_psa.getControlText() == "up to 50" || input_lrmv_psa.getControlText() < 0 || input_lrmv_psa.getControlText() > 50 || !isNumeric(input_lrmv_psa.getControlText()) ){ error_psa = 1; error = 1; } if ( input_lrmv_nodes.getControlText() == "up to 40" || input_lrmv_nodes.getControlText() < 0 || input_lrmv_nodes.getControlText() > 40 || !isNumeric(input_lrmv_nodes.getControlText()) ){ error_nodes = 1; error = 1; } if (combo_lrmv_cs.getControlText() == "Select"){ error_cs = 1; error = 1; } if (combo_lrmv_gsm.getControlText() == "Select"){ error_gsm = 1; error = 1; } if (error) { if (error_psa) alert("please fill in the PSA field properly"); else if (error_cs) alert("please fill in the Clinical Stage field properly"); else if (error_gsm) alert("please fill in the Gleason Sum field properly"); else if (error_nodes) alert("please fill in the Total Nodes field properly"); } else { var psa; var cs; var gsm; var nodes; var p,z, kE; psa = input_lrmv_psa.getControlText(); nodes = input_lrmv_nodes.getControlText(); if (combo_lrmv_cs.getControlText() == "T1c") cs = 0; if (combo_lrmv_cs.getControlText() == "T2") cs = 0.27208988; if (combo_lrmv_cs.getControlText() == "T3") cs = 2.00503629; if (combo_lrmv_gsm.getControlText() == "2 - 5") gsm = 0; if (combo_lrmv_gsm.getControlText() == "6") gsm = 0.29248698; if (combo_lrmv_gsm.getControlText() == "7") gsm = 1.80978177; if (combo_lrmv_gsm.getControlText() == "8 - 10") gsm = 2.41874491; kE = 2.718281828459045235360287471352; z = (0.02014919 * psa) + cs + gsm + (0.05390611 * nodes) - 4.73990958; p = 100 * (1 / (1 + Math.pow(kE,-z))); p = roundNumber(p,1); result_lrmv_1.setControlText("Your probability of having LNI using the total "); result_lrmv_2.setControlText("number of nodes removed and examined is"); result_lrmv_2b.setControlText(""+p+"%"); result_lrmv_3.setControlText("Please discuss this probability with your physician."); result_lrmv_4.setControlText("This percentage needs to be interpreted in context"); result_lrmv_5.setControlText("of your age, general health and several other"); result_lrmv_6.setControlText("considerations."); container.element().innerHTML = LRMVpageResult.join(""); tabs.setSelectedItems([1]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } input_lrmv_psa.onControlActivated = function(event){ if (input_lrmv_psa.getControlText() == "up to 50") { input_lrmv_psa.setControlText(""); } } input_lrmv_psa.onControlDeactivated = function(event){ if (input_lrmv_psa.getControlText() == "") { input_lrmv_psa.setControlText("up to 50"); } } input_lrmv_nodes.onControlActivated = function(event){ if (input_lrmv_nodes.getControlText() == "up to 40") { input_lrmv_nodes.setControlText(""); } } input_lrmv_nodes.onControlDeactivated = function(event){ if (input_lrmv_nodes.getControlText() == "") { input_lrmv_nodes.setControlText("up to 40"); } } // end of LRM RMV events //-------------------------------------------------------------- // LRM PLND events button_plnd_calculate.onClick = function(){ var error = 0; var error_psa = 0; var error_cs = 0; var error_gsm = 0; if ( input_plnd_psa.getControlText() == "up to 50" || input_plnd_psa.getControlText() < 0 || input_plnd_psa.getControlText() > 50 || !isNumeric(input_plnd_psa.getControlText()) ){ error_psa = 1; error = 1; } if (combo_plnd_cs.getControlText() == "Select"){ error_cs = 1; error = 1; } if (combo_plnd_gsm.getControlText() == "Select"){ error_gsm = 1; error = 1; } if (error) { if (error_psa) alert("please fill in the PSA field properly"); else if (error_cs) alert("please fill in the Clinical Stage field properly"); else if (error_gsm) alert("please fill in the Gleason Sum field properly"); } else { var psa; var cs; var gsm; var p,z, kE; psa = input_plnd_psa.getControlText(); if (combo_plnd_cs.getControlText() == "T1c") cs = 0; if (combo_plnd_cs.getControlText() == "T2") cs = 0.24215941; if (combo_plnd_cs.getControlText() == "T3") cs = 1.95725270; if (combo_plnd_gsm.getControlText() == "2 - 5") gsm = 0; if (combo_plnd_gsm.getControlText() == "6") gsm = 0.44515743; if (combo_plnd_gsm.getControlText() == "7") gsm = 1.89585633; if (combo_plnd_gsm.getControlText() == "8 - 10") gsm = 2.52844780; kE = 2.718281828459045235360287471352; z = (0.01638081 * psa) + cs + gsm - 3.73692396; p = 100 * (1 / (1 + Math.pow(kE,-z))); p = roundNumber(p,1); result_plnd_1.setControlText("Your probability of having LNI at extended "); result_plnd_2.setControlText("lymph node dissection is "); result_plnd_2b.setControlText(""+p+"%"); result_plnd_3.setControlText("Please discuss this probability with your physician."); result_plnd_4.setControlText("This percentage needs to be interpreted in context"); result_plnd_5.setControlText("of your age, general health and several other"); result_plnd_6.setControlText("considerations."); container.element().innerHTML = PLNDpageResult.join(""); tabs.setSelectedItems([1]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } input_plnd_psa.onControlActivated = function(event){ if (input_plnd_psa.getControlText() == "up to 50") { input_plnd_psa.setControlText(""); } } input_plnd_psa.onControlDeactivated = function(event){ if (input_plnd_psa.getControlText() == "") { input_plnd_psa.setControlText("up to 50"); } } // end of LRM PLND events //-------------------------------------------------------------- //-------------------------------------------------------------- // obturator events button_obt_calculate.onClick = function(){ var error = 0; var error_psa = 0; var error_cs = 0; var error_gsm = 0; if ( input_obt_psa.getControlText() == "up to 140" || input_obt_psa.getControlText() < 0 || input_obt_psa.getControlText() > 140 || !isNumeric(input_obt_psa.getControlText()) ){ error_psa = 1; error = 1; } if (combo_obt_cs.getControlText() == "Select"){ error_cs = 1; error = 1; } if (combo_obt_gsm.getControlText() == "Select"){ error_gsm = 1; error = 1; } if (error) { if (error_psa) alert("please fill in the PSA field properly"); else if (error_cs) alert("please fill in the Clinical Stage field properly"); else if (error_gsm) alert("please fill in the Gleason Sum field properly"); } else { var psa; var cs; var gsm; var p,z, kE; psa = input_obt_psa.getControlText(); if (combo_obt_cs.getControlText() == "T1c") cs = 0; if (combo_obt_cs.getControlText() == "T2") cs = -0.01964474; if (combo_obt_cs.getControlText() == "T3") cs = 0.83539179; if (combo_obt_gsm.getControlText() == "2 - 6") gsm = 0; if (combo_obt_gsm.getControlText() == "7") gsm = 1.73338296; if (combo_obt_gsm.getControlText() == "8 - 10") gsm = 3.14729676; kE = 2.718281828459045235360287471352; z = (0.01613545 * psa) + cs + gsm - 4.99685216; p = 100 * (1 / (1 + Math.pow(kE,-z))); p = roundNumber(p,1); result_obt_1.setControlText("Your probability of having LNI beyond"); result_obt_2.setControlText("the obturator nodes is "); result_obt_2b.setControlText(""+p+"%"); result_obt_3.setControlText("Please discuss this probability with your physician."); result_obt_4.setControlText("This percentage needs to be interpreted in context"); result_obt_5.setControlText("of your age, general health and several other"); result_obt_6.setControlText("considerations."); container.element().innerHTML = OBTpageResult.join(""); tabs.setSelectedItems([1]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } input_obt_psa.onControlActivated = function(event){ if (input_obt_psa.getControlText() == "up to 140") { input_obt_psa.setControlText(""); } } input_obt_psa.onControlDeactivated = function(event){ if (input_obt_psa.getControlText() == "") { input_obt_psa.setControlText("up to 140"); } } // end of obturator events //-------------------------------------------------------------- // DMAR events button_dmar_calculate.onClick = function(){ var error = 0; var error_cormo = 0; var error_age = 0; var error_aasv = 0; if ( input_dmar_cormo.getControlText() == "up to 11" || input_dmar_cormo.getControlText() < 0 || input_dmar_cormo.getControlText() > 11 || !isNumeric(input_dmar_cormo.getControlText()) ){ error_cormo = 1; error = 1; } if (combo_dmar_age.getControlText() == "Select"){ error_age = 1; error = 1; } if (combo_dmar_aasv.getControlText() == "Select"){ error_aasv = 1; error = 1; } if (error) { if (error_cormo) alert("please fill in the Cormobidity field properly"); else if (error_age) alert("please fill in the Age at RP field properly"); else if (error_aasv) alert("please fill in the Avg. An.. Surg. Vol. field properly"); } else { var cormo; var age; var aasv; var p,z, kE; cormo = input_dmar_cormo.getControlText(); if (combo_dmar_age.getControlText() == "40 - 68") age = 0; if (combo_dmar_age.getControlText() == "69+") age = 1.1516306; if (combo_dmar_aasv.getControlText() == "0.2 - 27.0") aasv = 0; if (combo_dmar_aasv.getControlText() == "27.1+") aasv = -1.9748448; kE = 2.718281828459045235360287471352; z = (0.2459623 * cormo) + age + aasv - 5.8656661; p = 100 * (1 / (1 + Math.pow(kE,-z))); p = roundNumber(p,1); result_dmar_1.setControlText("The odds of dying from any cause within 30"); result_dmar_2.setControlText("days of surgery are:"); result_dmar_2b.setControlText(""+p+"%"); result_dmar_3.setControlText("Please discuss this probability with your physician."); result_dmar_4.setControlText("This percentage needs to be interpreted in context"); result_dmar_5.setControlText("of your age, general health and several other"); result_dmar_6.setControlText("considerations."); container.element().innerHTML = DMARpageResult.join(""); tabs.setSelectedItems([2]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } input_dmar_cormo.onControlActivated = function(event){ if (input_dmar_cormo.getControlText() == "up to 11") { input_dmar_cormo.setControlText(""); } } input_dmar_cormo.onControlDeactivated = function(event){ if (input_dmar_cormo.getControlText() == "") { input_dmar_cormo.setControlText("up to 11"); } } // end of DMAR events //-------------------------------------------------------------- // YSAT events button_ysat_calculate.onClick = function(){ var error = 0; var error_cormo = 0; var error_age = 0; if ( input_ysat_cormo.getControlText() == "up to 12" || input_ysat_cormo.getControlText() < 0 || input_ysat_cormo.getControlText() > 12 || !isNumeric(input_ysat_cormo.getControlText()) ){ error_cormo = 1; error = 1; } if ( input_ysat_age.getControlText() == "between 55 and 95" || input_ysat_age.getControlText() < 55 || input_ysat_age.getControlText() > 95 || !isNumeric(input_ysat_age.getControlText()) || !isInt(input_ysat_age.getControlText()) ){ error_age = 1; error = 1; } if (error) { if (error_cormo) alert("please fill in the Cormobidity field properly"); else if (error_age) alert("please fill in the Age at Therapy field properly"); } else { var cormo; var age; var p,z, kE; cormo = input_ysat_cormo.getControlText(); age = input_ysat_age.getControlText(); kE = 2.718281828459045235360287471352; z = -4.26868908118702 + (age * 0.06107070266617) + (cormo * 0.14581304661238); var p10yRRP; var p10yXRT; p10yRRP = 100 * Math.pow( kE, Math.pow(kE,z+0.1489045385791) * Math.log(0.8198370562007) ); p10yXRT = 100 * Math.pow( kE, Math.pow(kE,z-0.3590188104580) * Math.log(0.3158026905329) ); p10yRRP = roundNumber(p10yRRP,1); p10yXRT = roundNumber(p10yXRT,1); result_ysat_1.setControlText("Your probability of 10-year survival:"); result_ysat_3.setControlText("with surgery is= "+p10yRRP+"%"); result_ysat_4.setControlText("with radiation is = "+p10yXRT+"%"); result_ysat_5.setControlText("Please discuss this probability with your physician."); result_ysat_6.setControlText("This percentage needs to be interpreted in context"); result_ysat_7.setControlText("of your age, general health and several other"); result_ysat_8.setControlText("considerations."); container.element().innerHTML = YSATpageResult.join(""); tabs.setSelectedItems([2]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } input_ysat_cormo.onControlActivated = function(event){ if (input_ysat_cormo.getControlText() == "up to 12") { input_ysat_cormo.setControlText(""); } } input_ysat_cormo.onControlDeactivated = function(event){ if (input_ysat_cormo.getControlText() == "") { input_ysat_cormo.setControlText("up to 12"); } } input_ysat_age.onControlActivated = function(event){ if (input_ysat_age.getControlText() == "between 55 and 95") { input_ysat_age.setControlText(""); } } input_ysat_age.onControlDeactivated = function(event){ if (input_ysat_age.getControlText() == "") { input_ysat_age.setControlText("between 55 and 95"); } } // end of YSAT events //-------------------------------------------------------------- // RPHT events button_rpht_calculate.onClick = function(){ var error = 0; var error_pt3 = 0; var error_rpgl = 0; var error_psm = 0; var error_age = 0; var error_rec = 0; if ( input_rpht_age.getControlText() == "between 45 and 95" || input_rpht_age.getControlText() < 45 || input_rpht_age.getControlText() > 95 || !isNumeric(input_rpht_age.getControlText()) ){ error_age = 1; error = 1; } if (combo_rpht_rpgl.getControlText() == "Select"){ error_rpgl = 1; error = 1; } if (combo_rpht_psm.getControlText() == "Select"){ error_psm = 1; error = 1; } if (combo_rpht_pt3.getControlText() == "Select"){ error_pt3 = 1; error = 1; } if (combo_rpht_rec.getControlText() == "Select"){ error_rec = 1; error = 1; } if (error) { if (error_pt3) alert("please fill in the pT3 field properly"); else if (error_rpgl) alert("please fill in the RP. Gl. 8-10 field properly"); else if (error_psm) alert("please fill in the +SM field properly"); else if (error_age) alert("please fill in the Age at HT field properly"); else if (error_rec) alert("please fill in Rec. Type field properly"); } else { var pt3; var rpgl; var psm; var age; var rec; var z, kE; age = input_rpht_age.getControlText(); if (combo_rpht_pt3.getControlText() == "Yes") pt3 = 0.89356720028427; if (combo_rpht_pt3.getControlText() == "No") pt3 = 0; if (combo_rpht_rpgl.getControlText() == "Yes") rpgl = 0.42900090658587; if (combo_rpht_rpgl.getControlText() == "No") rpgl = 0; if (combo_rpht_psm.getControlText() == "Yes") psm = -0.75996995905313; if (combo_rpht_psm.getControlText() == "No") psm = 0; if (combo_rpht_rec.getControlText() == "PSA Recurrance") rec = 0; if (combo_rpht_rec.getControlText() == "Loc Recurrance") rec = -0.07655341723188; if (combo_rpht_rec.getControlText() == "Dis Recurrance") rec = 0.89029717625269; kE = 2.718281828459045235360287471352; z = pt3 + rpgl + psm + rec - (0.04454821527397 * age) + 2.416862486016 ; var p2y = 100 * Math.pow( kE, Math.pow(kE, z-0.3003652718780) * Math.log(0.8900360258488) ); var p3y = 100 * Math.pow( kE, Math.pow(kE, z-0.2801426075930) * Math.log(0.7930717534326) ); var p4y = 100 * Math.pow( kE, Math.pow(kE, z-0.2531713961291) * Math.log(0.7216477172177) ); var p5y = 100 * Math.pow( kE, Math.pow(kE, z-0.2424504470484) * Math.log(0.6829880180810) ); p2y = roundNumber(p2y,1); p3y = roundNumber(p3y,1); p4y = roundNumber(p4y,1); p5y = roundNumber(p5y,1); result_rpht_1.setControlText("Odds of NOT dying of prostate cancer at"); result_rpht_2.setControlText("following times after starting hormone therapy:"); result_rpht_3.setControlText("2 years = "+p2y+"%"); result_rpht_4.setControlText("3 years = "+p3y+"%"); result_rpht_5.setControlText("4 years = "+p4y+"%"); result_rpht_6.setControlText("5 years = "+p5y+"%"); result_rpht_7.setControlText("Please discuss this probability with your"); result_rpht_8.setControlText("physician. This percentage needs to be"); result_rpht_9.setControlText("interpreted in context of your age, general"); result_rpht_10.setControlText("health and several other considerations."); container.element().innerHTML = RPHTpageResult.join(""); tabs.setSelectedItems([4]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } input_rpht_age.onControlActivated = function(event){ if (input_rpht_age.getControlText() == "between 45 and 95") { input_rpht_age.setControlText(""); } } input_rpht_age.onControlDeactivated = function(event){ if (input_rpht_age.getControlText() == "") { input_rpht_age.setControlText("between 45 and 95"); } } // end of RPHT events //-------------------------------------------------------------- // PREC events button_prec_calculate.onClick = function(){ var error = 0; var error_gsm = 0; var error_adj = 0; if (combo_prec_adj.getControlText() == "Select"){ error_adj = 1; error = 1; } if (combo_prec_gsm.getControlText() == "Select"){ error_gsm = 1; error = 1; } if (error) { if (error_gsm) alert("please fill in the Path Gl. Sum field properly"); else if (error_adj) alert("please fill in the Adjuvant XRT field properly"); } else { var gsm; var adj; var z, kE; if (combo_prec_adj.getControlText() == "Yes") adj = 1.77188558111711; if (combo_prec_adj.getControlText() == "No") adj = 0; if (combo_prec_gsm.getControlText() == "2 - 6") gsm = 0; if (combo_prec_gsm.getControlText() == "7") gsm = 0.94314408309415; if (combo_prec_gsm.getControlText() == "8 - 10") gsm = 2.24769079377347; kE = 2.718281828459045235360287471352; z = -1.01082483825502 + adj + gsm; var p2y = 100 * Math.pow( kE, Math.pow(kE, z-3.1991681059088) * Math.log(0.9128209977258) ); var p5y = 100 * Math.pow( kE, Math.pow(kE, z-1.8816561869930) * Math.log(0.8196650749803) ); var p10y = 100 * Math.pow( kE, Math.pow(kE, z-1.1514922458081) * Math.log(0.7524784392226) ); p2y = roundNumber(p2y,1); p5y = roundNumber(p5y,1); p10y = roundNumber(p10y,1); result_prec_1.setControlText("Your probability of NOT dying of prostate cancer"); result_prec_2.setControlText("after surgery and PSA recurrence is:"); result_prec_4.setControlText("after 2 years = "+p2y+"%"); result_prec_5.setControlText("after 5 years = "+p5y+"%"); result_prec_6.setControlText("after 10 years = "+p10y+"%"); result_prec_7.setControlText("Please discuss this probability with your physician."); result_prec_8.setControlText("This percentage needs to be interpreted in context"); result_prec_9.setControlText("of your age, general health and several other"); result_prec_10.setControlText("considerations."); container.element().innerHTML = PRECpageResult.join(""); tabs.setSelectedItems([4]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } // end of PREC events //-------------------------------------------------------------- // end of PDT events //-------------------------------------------------------------- function roundNumber(number,decimal_points) { if(!decimal_points) return Math.round(number); if(number == 0) { var decimals = ""; for(var i=0;i day0){ day_result = N + day0 - dayi ; monthi++; } if (monthi <= month0){ month_result = month0 - monthi; } if (monthi > month0){ month_result = 12 + month0 - monthi; yeari++; } year_result = year0 - yeari; result = day_result + (30 * month_result) + (365 * year_result); return result; } //-------------------------------------------------------------- // psab events button_psab_calculate.onClick = function(){ var error = 0; var error_dre = 0; var error_fpsa = 0; if ( input_psab_fpsa.getControlText() == "between 3.33 and 85" || input_psab_fpsa.getControlText() < 3.33 || input_psab_fpsa.getControlText() > 85 || !isNumeric(input_psab_fpsa.getControlText()) ){ error_fpsa = 1; error = 1; } if (combo_psab_dre.getControlText() == "Select"){ error_dre = 1; error = 1; } if (error) { if (error_dre) alert("please fill in the DRE field properly"); else if (error_fpsa) alert("please fill in the % Free PSA field properly"); } else { var age; var dre; var fpsa; var p,z, kE; fpsa = input_psab_fpsa.getControlText(); if (combo_psab_dre.getControlText() == "Suspicious") dre = 1; if (combo_psab_dre.getControlText() == "Normal") dre = 0; kE = 2.718281828459045235360287471352; z = -0.004483058 - (fpsa * 0.056679137) + (dre * 0.724297143); p = 100 * (1 / (1 + Math.pow(kE,-z))); p = roundNumber(p,1); result_psab_1.setControlText("The probability of finding prostate cancer"); result_psab_2.setControlText("during biopsy is"); result_psab_3.setControlText(""+p+"%"); result_psab_5.setControlText("Please discuss this probability with your physician."); result_psab_6.setControlText("This percentage needs to be interpreted in context"); result_psab_7.setControlText("of your age, general health and several other"); result_psab_8.setControlText("considerations."); container.element().innerHTML = PSABpageResult.join(""); tabs.setSelectedItems([0]); tabs.setItemText(["Before Diagnosis", "Before Treatment I", "Before Treatment II", "After Surgery", "After PSA Relapse", "Hormone failure"]); tabs.refresh(); } } input_psab_fpsa.onControlActivated = function(event){ if (input_psab_fpsa.getControlText() == "between 3.33 and 85") { input_psab_fpsa.setControlText(""); } } input_psab_fpsa.onControlDeactivated = function(event){ if (input_psab_fpsa.getControlText() == "") { input_psab_fpsa.setControlText("between 3.33 and 85"); } } // end of psab events //-------------------------------------------------------------- button_back1.onClick = function(){container.element().innerHTML = page1.join("");} button_back2.onClick = function(){container.element().innerHTML = page1.join("");} button_back3.onClick = function(){container.element().innerHTML = page1.join("");} button_back4.onClick = function(){container.element().innerHTML = page1.join("");} button_back5.onClick = function(){container.element().innerHTML = page1.join("");} button_back6.onClick = function(){container.element().innerHTML = page1.join("");} button_back7.onClick = function(){container.element().innerHTML = page2.join("");} button_back8.onClick = function(){container.element().innerHTML = page2.join("");} button_back9.onClick = function(){container.element().innerHTML = page2.join("");} button_back10.onClick = function(){container.element().innerHTML = LNIpage.join("");} button_back11.onClick = function(){container.element().innerHTML = LNIpage.join("");} button_back12.onClick = function(){container.element().innerHTML = LNIpage.join("");} button_back13.onClick = function(){container.element().innerHTML = page3.join("");} button_back14.onClick = function(){container.element().innerHTML = page3.join("");} button_back15.onClick = function(){container.element().innerHTML = page3.join("");} button_back16.onClick = function(){container.element().innerHTML = page3.join("");} button_back17.onClick = function(){container.element().innerHTML = page4.join("");} button_back18.onClick = function(){container.element().innerHTML = page4.join("");} button_back19.onClick = function(){container.element().innerHTML = page4.join("");} button_back20.onClick = function(){container.element().innerHTML = page4.join("");} button_back21.onClick = function(){container.element().innerHTML = page5.join("");} button_back22.onClick = function(){container.element().innerHTML = page5.join("");} button_back23.onClick = function(){container.element().innerHTML = page5.join("");} button_back25.onClick = function(){container.element().innerHTML = page5.join("");} button_back24.onClick = function(){container.element().innerHTML = page6.join("");} button_back26.onClick = function(){container.element().innerHTML = page2.join("");}